Nicoumalone tablets contain the active ingredient acenocoumarol (previously known as nicoumalone in the UK), which is a type of medicine called an oral anticoagulant. It is used to stop blood clots forming within the blood vessels. Blood clots normally only form to stop bleeding that has occurred as a result of injury to the tissues. The clotting process is complicated and begins when blood cells called platelets clump together at the site of damage and produce chemicals that activate clotting factors in the blood. Clotting factors are proteins that are produced by the liver. Vitamin K is essential for their production. The activated clotting factors cause a protein called fibrinogen to be converted into another called fibrin. Fibrin binds the platelets together, forming a blood clot. This is the bodyÆs natural way of repairing itself. Sometimes, however, a blood clot can form abnormally within the blood vessels. This is known as a thrombus and can be dangerous because the clot may detach and travel in the bloodstream, where it becomes known as an embolus. The clot may eventually get lodged in a blood vessel, thereby blocking the blood supply to a vital organ such as the heart, brain or lungs. This is known as a thromboembolism.Some people have an increased tendency for blood clots to form within the blood vessels. This is usually due to a disturbance in the blood flow within the blood vessels. For example, fatty deposits on the walls of the blood vessels (atherosclerosis) can disrupt the blood flow, giving a tendency for platelets to clump together and start off the clotting process. Slow blood flow in the leg and pelvic veins can also result in clots forming (deep vein thrombosis). These clots can break off and travel to the lungs (pulmonary embolism). A type of fast irregular heartbeat called atrial fibrillation can also disrupt blood flow and may lead to blood clots forming in the heart. Heart valve disease can have the same effect, particularly if artificial heart valves have been fitted. Clots in the heart can detach and travel to the brain, causing a stroke. Acenocoumarol is used to reduce the risk of blood clots forming inside the blood vessels in conditions such as these. Acenocoumarol works by preventing the vitamin K dependent production of the clotting factors described above. Acenocoumarol prevents the production of these clotting factors by inhibiting the action of vitamin K. Without these clotting factors fibrinogen cannot be converted into fibrin and blood clots are therefore less likely to occur.Acenocoumarol takes about three days to produce its full anticoagulant effect because, while it prevents the production of new clotting factors, it takes about this long for clotting factors that have already been produced to be used up. For this reason, when treating blood clots such as deep vein thrombosis (DVT) or pulmonary embolism, a faster acting injectable anticoagulant, such as a heparin, is often used as well to begin with.The anticoagulant effect of acenocoumarol is measured in terms of the prothombin time, which is the time taken for blood clotting to occur in a sample of blood to which calcium and a substance known as thromboplastin have been added. This time is expressed as the International Normalised Ratio (INR). Your doctor will take regular blood samples and adjust your dose of acenocoumarol as necessary to make your INR fall into the range that has been shown to be effective at preventing blood clots in your particular condition.What is it used for?Treating and preventing blood clots in the blood vessels, for example in the following cases:Preventing abnormal blood clots in conditions with increased risk, eg rheumatic heart disease, atrial fibrillation and after insertion of artificial (prosthetic) heart valves Treatment and prevention of blood clots lodged in the veins of the leg (deep vein thrombosis) Treatment and prevention of blood clots that have travelled to the lungs (pulmonary embolism)
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More About Acitrom:
Nicholas Piramal
More About Discount Pharmacy Site Quality RX:
Quality RX are a discount online pharmacy stocking 100's of products to purchase online with no proof of prescription required. Always consult a doctor. All drugs that they offer on their site are in their generic form, and listed by their brand name. Every drug in existence is given a generic name upon its creation. The most popular and mass marketed drugs are then given a copyright brand or trade name for sales purposes. This is very similar to the way actors use a stage name. Just as the actor is one person with two names, these drugs are one chemical with two names. Stage names and brand names serve the same purpose, for the public to identify and easily remember the specific drug. Some drugs supplied by online pharmacies are manufactured in India, home to an enormous pharmaceutical industry, largely owned and operated by US drug companies. Under international law, Indian patent law allows scientists to reverse-engineer the active molecule of brand name drugs using a different process than the original patent, thereby allowing these manufacturers to obtain a process patent of their own. These drugs, legally made and patented in India without huge development and advertising costs, can be sold legally worldwide, at a fraction of the cost of the name brand they duplicate. That is why Quality RX can offer their low prices. As a result, India has become the largest producer of generic drugs in the world, with a quality that meets all health and medical standards. Their pills and caps are factory machine sealed in bubble packaging, untouched by human hands. They accept both Visa Card and Mastercard as a form of payment. They apologise for any inconvenience caused by not offering more payment solutions.

Pack Sizes for discount
Acitrom:
Acitrom 1mg 200(2 x 100) Tablets
1mg 400(4 x 100) Tablets 1mg
100 Tablets 2mg 400(4 x 100) Tablets
2mg 200(2 x 100) Tablets 2mg
100 Tablets 4mg 200(2 x 100) Tablets
4mg 400(4 x 100) Tablets 4mg
100 Tablets
Generic Name for Acitrom: Generic Nicoumalone
Category for Acitrom: Prescription Drugs

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(Source: US Food and Drug Administration). Information on this site is provided
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UPDATE: Cadence i.d.'s generic challenger to Ofirmev.
The threat from Paddock Laboratories of Minneapolis comes five months after
San Diego company started selling its intravenous formulation of acetaminophen,
the active ingredient in Tylenol.
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